Theophylline therapy

Theophylline dosing information

Theo-24 is contraindicated in patients with a history of hypersensitivity to theophylline or other components in the product. Injectables. Some doctors inject chemicals into the fat layer below the skin to encourage breakdown and make cellulite less noticeable. This procedure is often called mesotherapy. The chemicals used include phosphatidylcholine, aminophylline, hormones, herbal extracts, vitamins, and minerals. Do not use this medication if you are allergic to theophylline. The volume of distribution is also increased during the third trimester. Monitor serum levels. The recommendations for the use of theophylline in pregnant women with asthma are similar to those used in nonpregnant adults National Heart, Lung, and Blood Institute Guidelines 2004. canada neotrex capsules neotrex

Common side effects of theophylline

Teratogenic effects were observed in animal reproduction studies. Theophylline crosses the placenta; adverse effects may be seen in the newborn. Theophylline extended-release tablets are contraindicated in patients with a history of hypersensitivity to Theophylline or other components in the product. Certain conditions have been identified as causes of reduced theophylline clearance. Decrease your cellulite using the latest science. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. eulexin therapy

How to take theophylline

Larger diazepam doses may be required to produce desired level of sedation. Methotrexate: May increase the serum concentration of Theophylline Derivatives. What should I avoid while taking theophylline Uniphyl?

Does theophylline interact with other medications

Theophylline tablets can be taken once a day in the morning or evening. It is recommended that Theophylline tablets be taken with meals. Patients should be advised that if they choose to take Theophylline tablets with food it should be taken consistently with food and if they take it in a fasted condition it should routinely be taken fasted. It is important that the product whenever dosed be dosed consistently with or without food. Avoid the Food Trigger. Try not to come into contact with the food you are allergic to. Avoiding food triggers can be challenging. It is important to always read food labels and, when dining out, ask how foods are prepared. provera



How to use theophylline

Make sure lab personnel and all your doctors know you use this drug. Tablets can be taken once a day in the morning or evening. It is recommended that Uniphyl be taken with meals. Patients should be advised that if they choose to take Uniphyl with food it should be taken consistently with food and if they take it in a fasted condition it should routinely be taken fasted. It is important that the product whenever dosed be dosed consistently with or without food. Quinolone-class adverse reactions: Although not reported in completed clinical studies with enoxacin, a variety of adverse events have been reported with other quinolones. Peptic ulcer disease: Use with caution in patient with peptic ulcer disease; use may exacerbate this condition. Cross-resistance with other quinolones has been demonstrated. ZYFLO or stop taking the medicine without talking to your doctor first. Additionally, GINA guidelines do not recommend oral theophylline for asthma in children 6 to 11 years of age. Smokers: Tobacco and marijuana smoking appears to increase the clearance of Theophylline by induction of metabolic pathways. Theophylline clearance has been shown to increase by approximately 50% in young adult tobacco smokers and by approximately 80% in elderly tobacco smokers compared to non-smoking subjects. Passive smoke exposure has also been shown to increase Theophylline clearance by up to 50%. Abstinence from tobacco smoking for one week causes a reduction of approximately 40% in Theophylline clearance. Careful attention to dose reduction and frequent monitoring of serum Theophylline concentrations are required in patients who stop smoking see . Use of nicotine gum has been shown to have no effect on Theophylline clearance. AUC and consequent increased beta-blocker activity. Nervous system side effects have included generalized seizures, most commonly in patients with elevated serum concentrations, although seizures have occurred at therapeutic concentrations. Theophylline may also cause nervousness and tremor at therapeutic dosages, which become worse as serum concentrations increase. Extravasation: Vesicant; ensure proper catheter or needle position prior to and during infusion. Avoid extravasation. Treatment of seizures: Because of the high morbidity and mortality associated with Theophylline-induced seizures, treatment should be rapid and aggressive. International Academy of Cosmetic Dermatology: “Cellulite. Your blood levels of theophylline may increase and cause harmful effects. If symptoms are controlled and current dosage is tolerated, maintain dose and recheck serum concentration at 6-12 month intervals. If symptoms are not controlled and current dosage is tolerated consider adding additional medications to treatment regimen. Digoxin: Enoxacin may raise serum digoxin levels in some individuals. If signs and symptoms suggestive of digoxin occur when enoxacin and digoxin are given concomitantly, physicians are advised to obtain serum digoxin levels and adjust digoxin doses appropriately.



What conditions does theophylline treat

Antacids containing aluminum hydroxide and magnesium hydroxide reduce the oral absorption of enoxacin by 75%. The oral bioavailability of enoxacin is reduced by 60% with coadministration of ranitidine. These agents should not be taken for 8 hours before or for 2 hours after enoxacin administration. Decreased and subsequent decreased were noted in rats and dogs treated with doses of enoxacin that produced plasma levels in the animals three times higher than those produced in humans at the recommended therapeutic dosage. The potential for enoxacin to affect spermatogenesis in male patients is unknown. Institute supportive care, including establishment of intravenous access, maintenance of the airway, and electrocardiographic monitoring. Serious side effects may be more likely in older adults taking theophylline. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Prakash M, Washburne JD "Theophylline and urinary retention. To avoid excessive caffeine intake, be careful when taking guarana along with other foods and supplements that contain caffeine, such as coffee and sodas. Therapy with theophyllines should be administered cautiously in patients presenting with one or more of these risk factors, and the dosage should be appropriately reduced to prevent toxicity. More intensive monitoring of serum theophylline concentrations may be required. benicar



Prescribing information for theophylline

Berlinger WG, Spector R, Goldberg MJ, Johnson GF, Quee CK, Berg MJ. Enhancement of theophylline clearance by oral activated charcoal. In patients with chronic obstructive pulmonary disease COPD clinical studies have shown that Theophylline decreases dyspnea, air trapping, the work of breathing, and improves contractility of diaphragmatic muscles with little or no improvement in pulmonary function measurements. Administer multiple dose oral activated charcoal and measures to control emesis. Product Information. Theo-Dur theophylline. This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden breathing problems. If sudden shortness of breath occurs, use your quick-relief inhaler as prescribed. Theophylline clearance are continued. Phenobarbital may cause respiratory depression, particularly in elderly patients and patients with COPD. The scored tablet may be split. Several studies have described the clinical manifestations of theophylline overdose and attempted to determine the factors that predict life-threatening toxicity. It flows down your throat and into a series of air passageways called bronchial tubes. Treatment with broad-spectrum antibacterial agents alters the normal of the and may permit overgrowth of clostridia. Genitourinary side effects have included urinary retention. Theophylline concentrations at above average doses have the greatest likelihood of experiencing large changes in serum Theophylline concentration in response to dosage changes. Human experience of acute overdose with zileuton is limited. Do not take these medications without talking to your doctor; they can increase the side effects of theophylline.



Indications and usage of theophylline

Uniphyl theophylline anhydrous tablet Tablets whether dosed in the morning or evening. International Journal of Dermatology: “Subcision: a treatment for cellulite. Dosage adjustment based on serum theophylline concentrations: Note: Recheck serum theophylline concentration 24 hours after dosage adjustment. Stamford, CT 06901-3431. March 17, 2004. Each bead is an individual extended-release delivery system. After dissolution of the capsules these beads are released and distributed in the gastrointestinal tract, thus minimizing the probability of high local concentrations of theophylline at any particular site. Severe cases, sometimes without previous warning, have led to cardiac arrhythmias, intractable seizures, and death. Theophylline may antagonize non-depolarizing neuromuscular blocking effects; possibly due to phosphodiesterase inhibition. May lower theophylline seizure threshold. Do not start or stop smoking without first talking to your doctor. changes the way your body uses theophylline, and you may need to use a different dose. What are the uses for theophylline? Theophylline serum concentrations are a significant predictor of arrhythmias. purchase glimepiride tabletas



What other drugs will affect theophylline

III are current as of February 9, 1995. Bernstein JE, Lorincz AL "Ethylenediamine-induced exfoliative erythroderma. Monitor the patient and obtain a serum Theophylline concentration in 2-4 hours to insure that the concentration is not increasing. Children 1-15 years and adults 16-60 years without risk factors for impaired clearance. How should I take ZYFLO? Distribution Once theophylline enters the systemic circulation, about 40% is bound to plasma protein, primarily albumin. Unbound theophylline distributes throughout body water, but distributes poorly into body fat. ZYFLO. This includes all prescription and nonprescription medicines. There are several readily identifiable causes of reduced theophylline clearance. Babies are especially at risk for developing high levels of theophylline in the blood. So they need their blood levels checked regularly. Slow-release theophylline has an even greater risk for causing side effects than the short-acting medicine. The symptoms of asthmatic bronchitis are a combination of the symptoms of bronchitis and asthma. Higher doses of Theophylline may be required to achieve desired effect. If the asthma has been under control for several months at a certain dose of medicine, the dose may be reduced. This can help find the least amount of medicine that will control the asthma.



Theophylline overdose

Patients should be instructed to take this medication each morning at approximately the same time and not to exceed the prescribed dose. Patient may experience agitation, insomnia, or polyuria. Have patient report immediately to prescriber signs of low potassium muscle pain or weakness, muscle cramps, or an abnormal heartbeat signs of high blood sugar confusion, fatigue, increased thirst, increased hunger, polyuria, flushing, fast breathing, or breath that smells like fruit muscle pain, muscle weakness, tachycardia, abnormal heartbeat, fast breathing, severe dizziness, passing out, severe anxiety, nausea, vomiting, severe diarrhea, abdominal pain, severe headache, confusion, seizures, or tremors HCAHPS. Guarana has among the highest concentrations of in any plant. The dosage is based on your medical condition, response to treatment, age, weight, lab tests theophylline blood levels and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Minton NA, Glucksman E, Henry JA. Prevention of drug absorption in simulated theophylline overdose. Elderly patients are at a significantly greater risk of experiencing serious toxicity from theophylline than younger patients due to pharmacokinetic and pharmacodynamic changes associated with aging. Pediatrics The clearance of theophylline is very low in neonates see . Theophylline clearance reaches maximal values by one year of age, remains relatively constant until about 9 years of age and then slowly decreases by approximately 50% to adult values at about age 16. Renal excretion of unchanged theophylline in neonates amounts to about 50% of the dose, compared to about 10% in children older than three months and in adults. The nature of acute toxicity of theophylline differs from chronic toxicity. Acute overdose is associated with higher theophylline concentrations and younger patients. In acute overdose the severity of toxicity is correlated with peak serum concentrations. Chronic overdosage is seen more commonly in older patients, and severe toxicity may occur with serum concentrations which are much lower than those seen in severe acute toxicity. In these patients, age is a predictor of severe toxicity. Not reported in a comparable manner. F in original carton. Protect from light. Do not use if discolored or if crystals are present. Shannon M "Predictors of major toxicity after theophylline overdose. Before making a dose increase to determine whether the serum concentration is sub-therapeutic in a patient who continues to be symptomatic. The chronicity and pattern of theophylline overdosage significantly influences clinical manifestations of toxicity, management and outcome. Some of the side effects that can occur with aminophylline may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. order triamterene capsules



ZYFLO, call your doctor immediately

Oriordan JI, Hutchinson J, Fitzgerald MX, Hutchinson M "Amnesic syndrome after theophylline associated seizures: iatrogenic brain injury. If the patient's symptoms are well controlled, there are no apparent adverse effects, and no intervening factors that might alter dosage requirements see and serum theophylline concentrations should be monitored at 6 month intervals for rapidly growing children and at yearly intervals for all others. Increasing the rate of Theophylline clearance by extracorporeal methods may rapidly decrease serum concentrations, but the risks of the procedure must be weighed against the potential benefit. Charcoal hemoperfusion is the most effective method of extracorporeal removal, increasing Theophylline clearance up to sixfold, but serious complications, including hypotension, hypocalcemia, platelet consumption and bleeding diatheses may occur. Hemodialysis is about as efficient as multiple-dose oral activated charcoal and has a lower risk of serious complications than charcoal hemoperfusion. Hemodialysis should be considered as an alternative when charcoal hemoperfusion is not feasible and multiple-dose oral charcoal is ineffective because of intractable emesis. Older adults may be more likely to have side effects from theophylline. Enoxacin is an inhibitor of the enzyme gyrase and is a bactericidal agent. Enoxacin may be active against pathogens resistant to drugs that act by different mechanisms. In patients with COPD clinical studies have shown that theophylline decreases dyspnea, air trapping, the work of breathing, and improves contractility of diaphragmatic muscles with little or no improvement in pulmonary function measurements. Ophthalmologic abnormalities, including cataracts and multiple punctate lenticular opacities, have been noted in patients undergoing treatment with enoxacin, as well as with some other quinolones, but have also been observed in patients receiving in comparative trials. In using multiple-dose therapy, levels of enoxacin and other quinolones were significantly higher than respective concentrations. The causal relationship, if any, of quinolones to lenticular abnormalities has not been established. Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region. The Drugs. Mayo Clinic: “Cellulite Treatment. What other drugs will affect theophylline Uniphyl? Caution is advised when using this drug in the elderly because they may be more sensitive to its effects. Careful monitoring of side effects and drug levels is recommended. Theophylline clearance see or if it is not feasible to monitor serum Theophylline concentrations.



Theophylline relief

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Theophylline brand names


Theophylline decreases phenytoin 40%

Fever, regardless of its underlying cause, can decrease the clearance of theophylline. Make sure laboratory personnel and all your doctors know you use this drug. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Tell your doctor if you have any major changes in your diet. Your doctor may need to adjust your dose. If the serum sample is drawn more or less than twelve 12 hours after the dose, the results must be interpreted with caution since the concentration may not be reflective of the peak concentration. In contrast, when signs or symptoms of theophylline toxicity are present, the serum sample should be obtained as soon as possible, analyzed immediately, and the result reported to the healthcare professional without delay. is silagra safe silagra

Side effects of theophylline

Serum theophylline concentrations may continue to increase after presentation of the patient for medical care as a result of continued absorption of theophylline from the gastrointestinal tract. Serial monitoring of serum theophylline serum concentrations should be continued until it is clear that the concentration is no longer rising and has returned to non-toxic levels. Abiraterone Acetate: May increase the serum concentration of CYP1A2 Substrates. It can liquefy fat, cut connective tissue to loosen puckering, boost growth and tightening, increase flow, and lessen fluid retention. Expect results to last at least 6 months.

Decreases renal clearance of theophylline

Riociguat: Theophylline Derivatives may enhance the hypotensive effect of Riociguat. Overdose symptoms may include severe forms of some of the side effects listed in this medication guide. What should I avoid while taking theophylline? Theophylline Oral Solution USP is contraindicated in patients with a history of hypersensitivity to theophylline or other components in the product. Once-Daily Dosing: The slow absorption rate of this preparation may allow once-daily administration in adult non-smokers with appropriate total body clearance and other patients with low dosage requirements. Once-daily dosing should be considered only after the patient has been gradually and satisfactorily titrated to therapeutic levels with q12h dosing. Once-daily dosing should be based on twice the q12h dose and should be initiated at the end of the last q12h dosing interval. etal.info nootropil

Theophylline ingredients

Frequency not defined. Adverse events observed at therapeutic serum levels. Treatment of Cardiac Arrhythmias. Bronchitis itself can be caused by a virus or bacteria, which are contagious. However, chronic asthmatic bronchitis typically is not contagious. There was a minimal, dose-related, statistically significant increase in micronuclei at high doses in mice. The significance of these findings, in the absence of effects in other test systems, is not established. Moderate-to-severe phototoxicity reactions have been observed in patients exposed to direct sunlight while receiving enoxacin or some other drugs in this class. Excessive sunlight should be avoided. Therapy should be discontinued if phototoxicity occurs.

Theophylline increases the force of contraction of diaphragmatic muscles. This action appears to be due to enhancement of calcium uptake through an adenosine-mediated channel. Ticlopidine: May increase the serum concentration of Theophylline Derivatives. Bottles of 100 NDC 0089-0342-10. Zileuton: May increase the serum concentration of Aminophylline. Management: Reduce aminophylline dose by 50% upon initiation of zileuton therapy. If aminophylline is added to existing zileuton therapy, use a lower starting dose. Monitor for increased theophylline serum concentrations and effects. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

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